The Paul G. Allen Frontiers Group, a bioscience research initiative, awarded UCLA’s Steve Horvath an Allen Distinguished Investigator award. This award is given to researchers conducting pioneering research in epigenetics, aging and evolution. Each investigator is funded at $1.5 million over three years, totaling $7.5 million in funding. See full article in UCLA Newsroom
Eric Kawaguchi, a second-year doctoral student of UCLA's Department of Biostatistics, was selected as one of the three winners of the Student/Post-Doc Poster Award at the 2017 Lifetime Data Science Conference at the University of Connecticut. His poster presentation was on large scale sparse Cox's regression with applications to large drug safety studies. Congratulations to Eric!
Not a senior moment--just a biologically older brain.
Research by Dr. Steve Horvath, a professor of human genetics and biostatistics at UCLA’s David Geffen School of Medicine and Fielding School of Public Health, that led to an epigenetic clock that tracks biological aging was covered May 22 and May 19 in respective stories by The Scientist and GenomeWeb about how people’s brain tissue ages at different rates. The epigenetic clock was also cited May 18 in a STAT News story about the death of Fox News’ former CEO, Roger Ailes.
Sudipto Banerjee, Professor and Chair of the Department of Biostatistics, and his coauthors are recipients of the American Statistical Association's Outstanding Statistical Application Award for 2017 for their paper, Non-separable Dynamic Nearest-Neighbor Gaussian Process Models for Spatio-Temporal Data With an Application to Particulate Matter Analysis1. This award, established in 1986, is to recognize the authors of papers that demonstrate an outstanding application of statistics in any substantive field. Award recipients will be presented with an engraved award and $1,000 that is divided evenly among the winners during the 2017 JSM in Baltimore, Maryland. The award is bestowed upon a distinguished individual or individuals based on the following criteria: (a) the impact of the statistical application in addressing a significant problem in a substantive field, and (b) the ingenuity and or novelty of the statistical treatment of the problem.
1Abhirup Datta, Sudipto Banerjee, Andrew O. Finley, Nicholas A. S. Hamm, and Martijn Schaap (2016). Non-separable Dynamic Nearest-Neighbor Gaussian Process Models for Spatio-Temporal DataWith an Application to Particulate Matter Analysis. Annals of Applied Statistics, 10: 1286-1316.
Juhyun Kim, Biostatistics PhD doctoral student, has been selected as a 2017-2018 recipient of the Genomic Analysis and Interpretation Training Program. The Genomic Analysis Training Program is funded by a NIH grant and supports UCLA pre-doctoral students whose goal is to conduct research in genomics. The program is designed to insure that students obtain an adequate biological, computational and statistical foundation to succeed in this important new, interdisciplinary field.
Dr. Janet Sinsheimer has been selected to receive the 2017 L. Adrience Cupples Awardfor Excellence in Teaching, Research, and Service in Biostatistics, given by Boston University. This annual award recognizes an internationally recognized statistician/biostatistician who has made significant contributions to the statistical sciences and whose academic achievements reflect the contributions to teaching, research, and service exemplified by Professor L. Adrienne Cupples. We are extremely proud of Dr. Sinsheimer and congratulate her on this honor. More information about the award can be found here.
Dr. Steve Horvath has developed a highly accurate molecular biomarker of aging that is known as "epigenetic clock". The epigenetic clock and its various applications have received considerable attention in the popular press. Here are some pieces highlighting his research.
"Latinos age slower than other ethnicities, UCLA study shows" http://newsroom.ucla.edu/releases/latinos-age-slower-than-other-ethnicities-ucla-study-shows. "Menopause, sleepless nights may make women age faster" http://newsroom.ucla.edu/releases/menopause-sleepless-nights-may-make-women-age-faster. "Brains of people with Down syndrome age faster, UCLA study discovers" http://newsroom.ucla.edu/releases/brains-of-people-with-down-syndrome-age-faster-ucla-study-discovers. "UCLA scientist uncovers biological clock able to measure age of most human tissues" http://newsroom.ucla.edu/releases/ucla-scientist-uncovers-biological-248950. Cover of Discover magazine Oct 2016. http://discovermagazine.com/2016/oct/what-it-takes-to-reach-100. LA Times article on the Hispanic paradox http://www.latimes.com/science/sciencenow/la-sci-sn-latinos-aging-20160817-snap-story.html. Nature News Feature: "Biomarkers and ageing: The clock-watcher" http://www.nature.com/news/biomarkers-and-ageing-the-clock-watcher-1.15014. LA Times article on the epigentic clock: http://articles.latimes.com/2013/oct/21/science/la-sci-age-cells-20131021. UCLA Fielding School of Public Health: Impact Stories http://ph.ucla.edu/about-fsph/impact-stories/newly-invented-biological-clock-improves-accuracy-measuring-aging. "Epigenetic clock predicts life expectancy, UCLA-led study shows" http://newsroom.ucla.edu/releases/epigenetic-clock-predicts-life-expectancy-ucla-led-study-shows. The Guardian: "Internal 'clock' makes some people age faster and die younger – regardless of lifestyle" https://www.theguardian.com/science/2016/sep/28/internal-clock-makes-some-people-age-quicker-and-die-younger-regardless-of-lifestyle. Nautilus Magazine: "Why You Can’t Help But Act Your Age" http://nautil.us/issue/42/fakes/why-you-cant-help-but-act-your-age
VANCOUVER, British Columbia, Oct. 18, 2016 /PRNewswire/ -- Zymo Research Corp. announced today, during the ASHG 2016 Annual Meeting, that it has obtained an exclusive license for a methylation age predictor, also known as Horvath's Clock, so named for Dr. Steve Horvath, a professor of human genetics and biostatistics at the David Geffen School of Medicine at UCLA and Fielding School of Public Health, who is the developer of the epigenetic clock. Dr. Horvath examined the relationship between DNA methylation and aging. The Horvath Clock uses sample DNA from any biological source (such as adipose tissue, bladder, blood, various organs, etc.), other than sperm, to measure DNA methylation based on 353 epigenetic markers from the human genome. The clock estimates the biological age of most human tissues and cell types.
The epigenetic clock can be used for forensic, consumer or academic applications. Dr. Graham Threadgill, Vice President of Global Marketing at Zymo Research said, "The Horvath Clock is an important part of Zymo Research's aging program. We plan to commercialize products in the future based on the epigenetic clock and other related markers. We are excited to be at the forefront of this new field of research and look forward to expanding Zymo's presence in the field of epigenetic analysis."
Dr. Horvath's research in 2013 led him down the path to learn more about the process of human aging and how to slow it down. His Horvath Clock is a tool that compares the biological age of any tissue to its chronological age with consistently accurate results. The epigenetic clock could be used in a broad range of research, such as cancer or stem cell, to offer researchers valuable insights about the biological age of tissues and cell types.
About Zymo Research Corporation
Zymo Research Corporation, also known as "The Epigenetics Company", is a privately held company based in Irvine, California, USA. Since its inception in 1994 it has been serving the academic and biopharmaceutical scientific communities by providing DNA and RNA purification products. Zymo Research was an early adopter in the field of epigenetics and offers a line of products used in DNA methylation detection and quantitation. In addition to the epigenetic and nucleic acid purification products, Zymo also provides genetic, epigenetic and transcriptome analysis services. For more information, please visit: www.zymoresearch.com/epigenetics.
All trademarks are the property of their respective owners. Zymo Research Corporation, the stylized logo, and the tagline "The Beauty of Science is to Make Things Simple" are trademarks of Zymo Research Corporation and are registered with the USPTO.
Read the original full article here.
Professor Rob Weiss will be giving the 2016 Seymour Geisser Distinguished Lecture at the University of Minnesota School of Statistics on Thursday October 27. The title of his talk is Analysis of Hierarchical Sexual Behavior Profiles over Time.
The seminar website can be found at: http://www.stat.umn.edu/seminars/geisser/
Congratulations to Dr. Gang Li whose article, "A General Joint Model for Longitudinal Measurements and Competing Risks Survival Data with Heterogeneous Random Effects" is one of the 4 top-cited articles published in the last 5 years. Dr. Li receives this award from Springer and Lifetime Data Analysis at the LIDA-IG meeting, August 2nd at the American Statistical Association's Joint Statistical Meeting in Chicago.